A New Era for Improving Human Health: Nutrigenomics

The needs of your patients are always our first concern. Metagenics was founded in 1983 with the mission of helping patients achieve their "genetic potential through nutrition." This visionary byline was adopted before the Human genome Project was even started. Now this science is called nutrigenomics—the discovery of how bioactive substances from food and other natural sources can serve as potent dietary signaling molecules to positively affect genetic expression.

Kinase Enzyme Function, Genetic Expression & Optimal Health

It's now accepted that a person's state-of-health arises from the dynamic interaction of environmental factors with his or her genetic uniqueness. These factors can positively or negatively impact people’s health; that is, the extent to which people will realize their genetic potential.

Kinomics, Nutrigenomics, Proteomics, and Metabolomics. It is now known that nutritional factors are actually signaling molecules that interact with a comprehensive enzyme system composed of over 540 kinase enzymes. This system of kinase enzymes is called the human kinome. The body relies on the kinome to transmit signals from our environment (e.g., food, stress, toxin exposure) to the genome. Thus, the kinase signaling system actually facilitates the nutrient influence on gene expression (nutrigenomics) and related downstream effects on protein synthesis (proteomics), and metabolism (metabolomics), as pictured below. As a result, a new patient-centered health care is emerging that will rely upon nutrition and other modifiable lifestyle factors that influence the kinome to help people achieve optimal genetic expression. This approach to health care is called Therapeutic Lifestyle Change (TLC) programs. TLC programs are advocated by the National Institutes of Health and other leading heath organizations as the first line of therapy in the treatment of common chronic health conditions.

The Future is Here

Metagenics has discovered and developed the first Selective Kinase Response Modulator (SKRMs) formulations that can balance the kinome, which can be set off balance by unhealthy lifestyle choices. SKRMs help to rebalance selective kinase activity—and thus support healthy kinomics, genomics, proteomics, and metabolomics. We are proud and excited to bring this new technology to our healthcare professional partners because we know it provides them better tools for improving the health of their patients, and advancing the opportunity for everyone to achieve his or her genetic potential through nutrition.